International Conference on Novel Mental Health Treatments
13 October 2026, Prague, Czechia
SCALE takes place at a decisive moment for the future of mental health care. Research is advancing rapidly, clinical evidence is growing, and innovative approaches, including psychedelic-assisted therapies, are gaining recognition from regulators. But evidence alone is no longer enough. The challenge now is how to translate scientific progress into real-world access. How to build effective regulatory frameworks, align research with clinical practice, and connect innovation with payers and public institutions. Ultimately, the goal is clear - to ensure that novel mental health treatments reach the patients who need them most.
SCALE brings together leading scientists, clinicians, policymakers, insurers, investors, philanthropists, and international experts to address this challenge. The conference focuses on key questions shaping the field today, from strengthening psychological resilience in times of crisis and responding to war-related trauma, to understanding global trends in psychiatric care, designing regulatory pathways, and advancing discussions on cost-effectiveness and reimbursement.
SCALE is about the next phase of mental health innovation - moving from evidence to access, and turning progress into real impact.
As the debate on novel mental health treatments moves from scientific research towards implementation, the role of Member States is becoming increasingly important. Across Europe, governments, regulators, clinicians, and researchers are beginning to explore how innovative therapies can be safely integrated into healthcare systems, including through reimbursement schemes, clinical guidelines, and national mental health strategies. This creates a growing need for the exchange of best practices, regulatory experience, and evidence-based policy approaches between Member States.
In this context, the Czech Republic is emerging as one of the most advanced and closely watched examples in Europe. Czechia combines cutting-edge research, internationally recognised experts, and a rapidly developing ecosystem of specialised mental health and psychedelic clinics. At the same time, it has demonstrated a willingness to engage with complex regulatory questions. In 2024, the Czech Republic adopted a psychomodulatory law establishing a legal framework for psychomodulatory substances, followed in 2025 by parliamentary approval of the medical use of psilocybin. Additional steps include reimbursement schemes for ketamine-assisted therapy, and currently the preparation of secondary legislation, and the development of national cost-effectiveness studies on psilocybin-assisted therapy.
The Czech approach reflects a broader post-1989 tradition of evidence-based policymaking and openness to innovation in healthcare. It also responds to increasingly urgent societal challenges, including the growing PTSD burden linked to the war in Ukraine and wider security crises across Europe. By combining research excellence, clinical innovation, and regulatory ambition, Czechia is positioning itself as a European hub for responsible mental health innovation and as a valuable source of experience for other Member States navigating similar challenges.
08.45–09.30
Registration and Welcome Coffee
09.30–10.00
Opening Remarks
10:00–10.30
Keynote Speech
10.30–11.30
Building a Pathway for Novel Mental Health Treatments: Czech Model
11.30–12.00
Cost-effectiveness of Psilocybin-Assisted Therapy (Case Studies)
12.00–13.00
Lunch
13.00–14.00
PTSD Treatment in USA: From Tijuana to Oval Office
14.00–15.00
PTSD Treatment in Europe: EU, Member States and Frontline Regions
15.00–15.30
Coffee Break
15.30–16.45
Healthcare Ecosystem: Providers, Manufacturers and Companies
16.45–17.45
Approaching Paradigm Shift: Therapeutic Guidelines
17.45–18.15
Coffee Break
18.15–19.15
Women’s Mental Health: Birth, Maternal Mental Health and Trauma
19.15–19.20
Closing Remarks
20.00
Informal Networking
08.45–09.30
Registration and Welcome Coffee
09.30–10.15
Opening Remarks
09.30–10.15
Legislative Path Towards Psychedelic Therapy for Veterans in the US
11.00–12.00
Increasing the Psychological Resilience of Society in Times of Crisis
12.00–13.00
Lunch
TBC
12 October 2026
(hosted by EPIC)
Frontline: PAT, War in Ukraine and EU Funding

More details coming soon.
TBC
14 October 2026
Cost: Can PAT be cheaper for healthcare systems?

More details coming soon

The conference will take place at the Ball Game Hall (Míčovna) located within the historic Prague Castle - one of Europe’s most significant cultural and political landmarks. Set in the Royal Garden, the venue offers a unique combination of history and architecture, all just a short walk from the Czech Parliament.
Registrations will open in July 2026. Participation is free of charge, but capacity is limited. Your place is confirmed only after receiving a confirmation email from the organizers.
The conference will be conducted in English and Czech, with simultaneous interpretation available. Catering will be provided throughout the day.
If you have any questions, please contact the organisers at secretariat@scaleprague.eu.

The Ball Game Hall of the Prague Castle is easily accessible by public transport.
From the “Pražský hrad” tram stop (tram no. 22 or 23): Head towards Prague Castle. After passing the Lví dvůr restaurant, turn left through the iron gate into the Royal Garden.
From the metro "Malostranská" stop (either a 15-minute walk towards the Prague Castle or tram no. 22 or 23 to tram stop "Pražský hrad")
Take a look at the atmosphere of the conference from previous years.




